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Our top choices for O Brien hotels

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (204 reviews)
"Very happy to have stayed here. Great place, clean well designed, pretty and with all the amenities ready to use and working. Im glad I choose this place and highly recommend it."
United States
Andy
The price is AU$335
includes taxes & fees
5 May - 6 May
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (708 reviews)
"Great counters in the bathroom!! Loved the served breakfast and dinner!"
United States
Wendy
The price is AU$98
includes taxes & fees
17 May - 18 May
Super 8 by Wyndham Lake City

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (18 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
The price is AU$261
includes taxes & fees
17 May - 18 May
Vista Verde Farm Retreat

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (504 reviews)
"The property has convenient location. Clean hotel and great services."
United States
IVETTE
The price is AU$149
includes taxes & fees
24 May - 25 May
Hampton Inn & Suites Alachua I-75

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (666 reviews)
"It's a great place to stay if you're going to a festival at the spirit of Suwanee music Park "
United States
Elizabeth
The price is AU$104
includes taxes & fees
19 May - 20 May
Quality Inn White Springs Suwanee

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (242 reviews)
"Enjoyable stay"
United States
Warren J
The price is AU$182
includes taxes & fees
10 May - 11 May
Courtyard By Marriott Lake City

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (605 reviews)
"Lovely stay with spacious, comfortable rooms—perfect for relaxation! 🌟 Highly recommend for anyone seeking quality accommodation. While the pool was temporarily closed and bathroom sink pressure low, these minor issues didn't overshadow the overall excellent experience. Confidence in future improvements makes it easy to choose this place again. 😊🔧"
United States
Gilberto
The price is AU$102
includes taxes & fees
14 May - 15 May
Palms Garden Inn

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.0 out of 10, Very good, (154 reviews)
"Staff was very nice"
United States
Susan
The price is AU$105
includes taxes & fees
3 May - 4 May
Motel 6 – Lake City, Fl – Medical Center

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,001 reviews)
"Low cost but worth it"
United States
Michael
The price is AU$95
includes taxes & fees
3 May - 4 May
Days Inn by Wyndham Lake City I-10

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"Great location, very nice staff. Rooms was clean and nice "
United States
tonya
The price is AU$105
includes taxes & fees
7 May - 8 May
Americas Best Value Inn Lake City

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay, nice area"
United States
Jennifer
The price is AU$149
includes taxes & fees
10 May - 11 May
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (584 reviews)
"Regal inn was very neat and clean "
United States
Jennifer
The price is AU$86
includes taxes & fees
7 May - 8 May
Regal Inn

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (28 reviews)
"Staff was very helpful and attentive room was great great location "
United States
Madeline
The price is AU$60
includes taxes & fees
1 May - 2 May
Suwannee River Rendezvous

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,003 reviews)
"Great staff breakfast and room"
United States
Cynthia
The price is AU$127
includes taxes & fees
6 May - 7 May
Quality Inn Lake City

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (183 reviews)
"The parking was easy, and it’s a beautiful place. We really liked the history and decor, and the common spaces were a plus!"
United States
LEYA
The price is AU$207
includes taxes & fees
7 May - 8 May
The Blanche

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"The staff was very nice, breakfast was good and they kept a watch on to replace any items that needed. The room was clean, the beds comfortable. We had a wonderful stay."
United States
Evelin
The price is AU$185
includes taxes & fees
10 May - 11 May
Comfort Suites Lake City

Gateway Inn

Gateway Inn
2.5 star property
Lake City
7.8 out of 10, Good, (180 reviews)
"Great place"
United States
Teresa
The price is AU$91
includes taxes & fees
30 Apr - 1 May
Gateway Inn

< 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
10.0 out of 10, Exceptional, (1 review)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
The price is AU$543
includes taxes & fees
7 May - 8 May
< 1 Mi From Suwannee River, Hideaway w/ Lanai

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,001 reviews)
"Good hotel for the price."
United States
John
The price is AU$99
includes taxes & fees
3 May - 4 May
Days Inn by Wyndham Lake City I-75

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (433 reviews)
"Wonderful staff nice location clean rooms"
United States
Wayne
The price is AU$155
includes taxes & fees
13 May - 14 May
BlueGem Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

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Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Americas Best Value Inn Lake City. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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