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Our top choices for O Brien hotels

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.2 out of 10, Good, (698 reviews)
"Clean room, friendly staff, fantastic food!"
United States
John
The price is AU$103
includes taxes & fees
12 Mar - 13 Mar
Super 8 by Wyndham Lake City

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (186 reviews)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is AU$280
includes taxes & fees
30 Mar - 31 Mar
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,038 reviews)
"Great place to stay"
United States
Jack
The price is AU$130
includes taxes & fees
15 Mar - 16 Mar
Best Western Plus Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,000 reviews)
"The staff is great"
United States
Tana
The price is AU$177
includes taxes & fees
1 Apr - 2 Apr
Comfort Suites Lake City

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,000 reviews)
"Nice quiet property. They had scaled back some breakfast options but a good deal. "
United States
Dors
The price is AU$95
includes taxes & fees
15 Mar - 16 Mar
Days Inn by Wyndham Lake City I-10

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (593 reviews)
"Clean and nice staff "
United States
apollo
The price is AU$103
includes taxes & fees
12 Mar - 13 Mar
Palms Garden Inn

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.0 out of 10, Very good, (118 reviews)
"Dog friendly and price."
United States
John
The price is AU$106
includes taxes & fees
15 Mar - 16 Mar
Motel 6 – Lake City, Fl – Medical Center

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (175 reviews)
"Excellent Hotel! "
United States
jim
The Blanche

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (209 reviews)
"Great hotel "
United States
Guillermo
The price is AU$160
includes taxes & fees
22 Mar - 23 Mar
Fairfield Inn & Suites Lake City

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (16 reviews)
"The property is great and I had a fabulous 3 night stay. Ana was fantastic and gave great suggestions for things to do in the area. Loved the location, pet friendly and beautiful. Would came back again. "
United States
Jennie
The price is AU$275
includes taxes & fees
12 Mar - 13 Mar
Vista Verde Farm Retreat

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (223 reviews)
"Place was impeccable and fairly new. Only complaint were the beds and their hardness"
United States
jon
The price is AU$167
includes taxes & fees
22 Mar - 23 Mar
Courtyard By Marriott Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean and staff was very kind "
United States
Rosemary
The price is AU$172
includes taxes & fees
15 Mar - 16 Mar
Tru by Hilton Lake City

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (490 reviews)
"We visited family in the area and stayed here, hotel was clean, quiet, staff was great and room was so comfortable and spacious for our family of 5. Will definitely stay again!"
United States
Libbi
The price is AU$180
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Alachua I-75

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (643 reviews)
"Hotel is an older facility but room was clean and staff were exceptionally friendly and professional."
United States
Wayne
The price is AU$105
includes taxes & fees
25 Mar - 26 Mar
Quality Inn White Springs Suwanee

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,000 reviews)
"The room was clean and comfortable. The parking and surrounding area were good. Staff was friendly. "
United States
Lars
The price is AU$100
includes taxes & fees
15 Mar - 16 Mar
Days Inn by Wyndham Lake City I-75

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,002 reviews)
"Nice quiet and comfortable hotel a little gem."
Canada
Tim
The price is AU$106
includes taxes & fees
15 Mar - 16 Mar
Americas Best Value Inn Lake City

TownePlace Suites by Marriott Lake City

TownePlace Suites by Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (126 reviews)
"Good hotel"
United States
Frank
The price is AU$220
includes taxes & fees
15 Mar - 16 Mar
TownePlace Suites by Marriott Lake City

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (418 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is AU$118
includes taxes & fees
15 Mar - 16 Mar
BlueGem Motel

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (995 reviews)
"Staff were great and room was clean and comfortable "
Canada
Ethan
The price is AU$135
includes taxes & fees
18 Mar - 19 Mar
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,087 reviews)
"Excellent place to stay."
United States
Donovan
The price is AU$165
includes taxes & fees
15 Mar - 16 Mar
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Recent Reviews in O Brien

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Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Offers buffet, an outdoor pool and complimentary high-speed (wired) Internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Lafayette Blue Springs State Park and Lake City Mall in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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