O Brien Hotel & Accommodation Deals 2026 from AU$93 - Compare prices by date

A calm river with clear water, surrounded by dense trees and rocky banks.

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Our top choices for O Brien hotels

A spacious living area with a grey sofa, a coffee table, and a TV stand.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

A hotel entrance with a covered walkway, palm trees, and a clear sky.

A modern kitchen with light wood cabinets, granite countertops, and stainless steel appliances. There are signs on the wall advertising different coffee brands.

1. Best Western Plus Lake City

Lake City

William

AU$127

includes taxes & fees

20 Sept - 21 Sept

A covered outdoor area with a paved walkway, benches, and potted plants.

A bedroom with a bed, a desk, a chair, and a ceiling fan.

A compact RV kitchen with wooden cabinets, a microwave, a stove, and a sink.

A grassy area with a picnic table, a car parked in front of a building with a sloped roof, and trees with hanging moss.

2. Cindys Motel

Mayo

Diane

AU$133

includes taxes & fees

8 Sept - 9 Sept

A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

A modern living room with a sectional sofa, a round coffee table, a hanging chair, and a flat-screen TV on a glass stand.

A modern hotel lobby with a fireplace, seating areas, and a bar.

3. Comfort Suites Lake City

Lake City

KHAJA

AU$145

includes taxes & fees

23 Sept - 24 Sept

An indoor swimming pool with clear water, surrounded by glass doors and windows, and a wooden deck area.

An outdoor patio area with a sectional sofa, chairs, a coffee table, and a fire pit.

A modern living room with two green sofas, a white coffee table, and a flat-screen TV mounted on the wall.

A modern dining area with multiple tables and chairs, a kitchen in the background, and a 'Hello Fall' sign on the wall.

4. Fairfield Inn & Suites Lake City

Lake City

Thomas

AU$161

includes taxes & fees

16 Sept - 17 Sept

A hotel pool area with lounge chairs and umbrellas, a pool with metal railings, and a building with multiple floors and large windows.

A Hampton Inn & Suites hotel with a modern design, featuring a prominent red sign, a covered entrance, and a parking area.

A hotel with a blue and white facade, a covered entrance, and a parking lot.

5. Hampton Inn & Suites Lake City

Lake City

tracy

AU$179

includes taxes & fees

6 Sept - 7 Sept

A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

A modern kitchen area with a coffee station, including a coffee machine, cups, and a toaster.

A modern restaurant with a long counter, multiple seating options including red and yellow chairs, and a large window providing a view.

A hotel room with a large bed, a sofa, a desk, and a wall with a geometric pattern.

6. La Quinta Inn & Suite by Wyndham Lake City

Lake City

Nadia

AU$142

includes taxes & fees

6 Sept - 7 Sept

A hotel room with a large bed, a desk with a computer, a television, and a window with curtains.

A restaurant with a yellow accent wall, white tiled floor, and black and blue chairs.

A swimming pool with lounge chairs and umbrellas, surrounded by a brick building with balconies and palm trees.

An aerial view of a hotel with a swimming pool, parking lot, and surrounding greenery.

7. Super 8 by Wyndham Lake City

Lake City

Igor

AU$103

includes taxes & fees

8 Sept - 9 Sept

A self-service beverage station with a variety of drinks, snacks, and a refrigerated section.

A modern interior with two red chairs and a small table, large windows, and hanging pendant lights.

An outdoor patio with a stone fire feature, blue cushioned seating, and a grill.

A modern hotel with a flat roof, multiple windows, and a covered entrance.

8. Tru by Hilton Lake City

Lake City

Kelly

AU$171

includes taxes & fees

4 Oct - 5 Oct

A hotel with a covered entrance, a sign indicating it is a Holiday Inn Express, and a well-maintained lawn area.

A reception area with a counter, seating, and a fireplace.

A hotel room with a bed, a desk with a lamp, a television, and a microwave.

A hotel with a swimming pool, multiple windows, and a sign indicating no diving.

9. Holiday Inn Express & Suites Live Oak by IHG

Live Oak

Trisha

AU$162

includes taxes & fees

13 Sept - 14 Sept

A multi-story hotel with a prominent entrance, palm trees, and a green-lit sign indicating the name.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a changing room area.

A spacious lobby with multiple seating areas, a bar, and a large window with a view.

A fitness center with treadmills, elliptical machines, and a weight machine.

10. Holiday Inn & Suites Lake City by IHG

Lake City

Renee

AU$153

includes taxes & fees

6 Sept - 7 Sept

A spacious lobby with a high ceiling, a large window, a dining area with green chairs, and a black door leading outside.

A reception area with a counter, a coffee machine, and a potted plant.

A white building with multiple windows and a sign that reads 'Quality Inn.'

A hotel dining area with tables and chairs, a reception desk, and a kitchen in the background.

11. Quality Inn Lake City

Lake City

Lucille

AU$122

includes taxes & fees

13 Sept - 14 Sept

An aerial view of a campground with RVs, a swimming pool, and tennis courts.

A wooden cabin with a porch, a front door, and a small window.

A serene lakeside campsite with picnic tables and chairs.

A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

12. Suwannee River Rendezvous

Mayo

Beth

AU$169

includes taxes & fees

8 Sept - 9 Sept

An outdoor patio with a stone fire pit, grey cushioned seating, and wicker ottomans.

A modern hotel room with a bed, a desk with a computer, a TV, and a lamp.

A modern hotel with a two-story structure, a covered outdoor seating area, and a parking lot with marked spaces.

A modern hotel lobby with a reception desk, seating areas, and a large screen.

13. Home2 Suites by Hilton Lake City

Lake City

William

AU$180

includes taxes & fees

6 Sept - 7 Sept

A modern kitchen with a large window, a flat-screen TV, and a coffee machine.

A hotel lobby with a dining area, a reception desk, and a view of the outside.

A reception area with a tiled counter, a computer, a sign reading 'Quality,' and two decorative vases.

A hotel with a swimming pool, white lounge chairs, and a fenced area.

14. Quality Inn White Springs Suwanee

White Springs

Pennee

AU$99

includes taxes & fees

27 Sept - 28 Sept

A picnic table with a potted plant, located in a grassy area with a tree and a road in the background.

A living room with a black leather sofa, a wooden coffee table with a plant, and framed pictures on the wall.

A hotel lobby with a reception desk, a clock, a plant, a water dispenser, and a coffee station.

A hotel room with two beds, a nightstand with a phone and remote, and a patterned curtain.

15. Americas Best Value Inn Lake City

Lake City

Larissa

AU$108

includes taxes & fees

6 Sept - 7 Sept

A hotel room with two beds, a TV, a desk, and a painting of a sunset.

A hotel room with a large bed, a bedside table, a nightstand, a window, and a bathroom with a toilet and sink.

A kitchen with a black refrigerator and a microwave on a wooden shelf.

A swimming pool with lounge chairs, a small pool house, and a yellow multi-story building with balconies.

16. Days Inn by Wyndham Lake City I-75

Lake City

Wilberd

AU$99

includes taxes & fees

6 Sept - 7 Sept

A multi-story hotel with a modern design, featuring a prominent entrance and a parking area.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A reception area with two wooden reception desks, a wall-mounted decorative piece, and a refrigerator stocked with beverages.

17. Courtyard By Marriott Lake City

Lake City

Tonya

AU$169

includes taxes & fees

13 Sept - 14 Sept

A hotel reception area with a reception desk, seating area, and a view of the parking lot.

A hotel room with two beds, a bedside table with a lamp, a phone, and a window with curtains.

A reception area with a wooden floor, a reception desk, a seating area with chairs, and a view through the glass doors to the outside.

A compact room with a flat-screen TV on a wooden cabinet, a microwave on a small black stand, a chair, and a mirror with a light above it.

18. Econo Lodge Live Oak

Live Oak

James

AU$112

includes taxes & fees

14 Sept - 15 Sept

An outdoor patio area with wicker chairs, a round table, and a fire pit.

A modern interior with a sofa, round tables, and chairs, a TV mounted on the wall, and a patterned wall.

A modern interior with a dark wood desk, a blue chair, a sofa, and a patterned rug.

A hotel room with a bed, a sofa, a small table, a wardrobe, and a kitchenette.

19. TownePlace Suites by Marriott Lake City

Lake City

Jennifer

AU$195

includes taxes & fees

6 Sept - 7 Sept

A wooden bar area with a ceiling fan, concrete pillars, and a view of the outdoors.

20. Suwannee River Retreat: Pet Friendly, Private Dock

Branford

AU$848

includes taxes & fees

14 Sept - 15 Sept

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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Recent Reviews in O Brien

Fairfield Inn & Suites Lake City

10/10 Excellent

"Room was clean, breakfast good, restaurants near by and they had cookies."

Hampton Inn & Suites Lake City

10/10 Excellent

"I’m diabetic so when I went down for breakfast and saw a sign that said “if you have dietary needs let us know “ I was ecstatic! Every other hotel we stayed at as we traveled offered very little that I could eat. I will definitely be staying here again"

La Quinta Inn & Suite by Wyndham Lake City

10/10 Excellent

"It was good,"

Tru by Hilton Lake City

8/10 Good

"Everything was wonderful except they charged me twice for my dog and they said that an emotional support dog is not considered a service dog to my plate. I don’t feel that is fair to me or my dog. I don’t know anywhere without my dog."

Comfort Suites Lake City

10/10 Excellent

"Spacious king size room laid out for business travelers. The couch was comfortable and set up for electronics."

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Extraordinary experience!!! We loved the place, the atmosphere. The cabin was amazing"

Quality Inn & Suites Live Oak I-10 Exit 283

10/10 Excellent

"We have relatives in Live Oak and stay at this Inn on a regular basis. Their services just get better each time we are there."

Hampton Inn & Suites Alachua I-75

10/10 Excellent

"Pasamos una estancia maravillosa lo recomendamos 100%"

More cheap accommodation in O Brien

Days Inn by Wyndham Lake City I-10

3430 N Us Highway 441 Lake City FL

AU$93

6 Sept - 7 Sept

includes taxes & fees

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL

AU$122

13 Sept - 14 Sept

includes taxes & fees

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

AU$127

20 Sept - 21 Sept

includes taxes & fees

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL

AU$145

23 Sept - 24 Sept

includes taxes & fees

9.4/10 Exceptional! (1,000 reviews)

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane Alachua FL

AU$166

4 Oct - 5 Oct

includes taxes & fees

9.4/10 Exceptional! (553 reviews)

Tru by Hilton Lake City

284 NW Centurion Court Lake City FL

AU$171

4 Oct - 5 Oct

includes taxes & fees

9.2/10 Wonderful! (1,005 reviews)

Find out more about O Brien

Top reasons to visit O Brien

Stunning Natural Scenery: O'Brien boasts breathtaking landscapes perfect for outdoor activities like hiking and nature walks.
Outdoor Adventures: Enjoy thrilling experiences such as jet skiing and leisurely river walks in a picturesque setting.
Family-Friendly Atmosphere: The charming neighbourhoods cater to families, making it ideal for a memorable holiday.
Diverse Accommodation Options: From pet-friendly motels to historic hotels, there's something for every traveller's needs.
Cultural Experiences Nearby: A short drive to downtown San Antonio offers vibrant dining and cultural attractions.

Find great hotels near O Brien

Discover the charm of O'Brien, Florida, where a variety of accommodation options await you. From inviting motels to historic hotels, this quaint location caters to all travellers. Whether you seek pet-friendly lodgings, a welcoming atmosphere for LGBTQIA guests, or convenient amenities for business travel, O'Brien has it all. Explore the picturesque O'Brien Riverwalk Boutique Hotel and other delightful stays that promise a memorable holiday experience.

Americas Best Value Inn Lake City: Located 29km from O Brien, Americas Best Value Inn Lake City is a charming motel with a guest rating of 8.6. This property is an excellent choice for travellers seeking a pet-friendly environment, offering amenities such as a fee-waived service for service animals and specific pet policies allowing certain pets on-site. Guests appreciate the welcoming atmosphere and comfortable accommodations, making it an ideal place to unwind after a day of exploration.
Baymont by Wyndham Lake City I-75: Situated 29km from O Brien, Baymont by Wyndham Lake City I-75 is a versatile hotel designed to cater to families, business travellers, and pet owners alike. The hotel provides essential amenities for children, including complimentary cribs, ensuring a convenient stay for families. With a pet-friendly policy that includes restrictions and fees, this property balances comfort and practicality, making it an inviting option for various types of visitors.
Comfort Suites Lake City: Comfort Suites Lake City, located 29km from O Brien, boasts an impressive guest rating of 9.4. This hotel is tailored for business travellers, offering a range of facilities designed to support work needs while ensuring a comfortable stay. The well-appointed rooms and attentive service create a professional yet relaxed atmosphere, making it a preferred choice for those visiting the area for business purposes.

Where to stay near O Brien

For those seeking outdoor adventures and breathtaking scenery, O'Brien, Florida, presents an idyllic getaway. Experience the charm of family-friendly neighbourhoods while enjoying luxurious accommodations with friendly staff at affordable rates. Explore the nearby picturesque landscapes, perfect for hiking and nature walks. Just a short drive away, discover the vibrant atmosphere of downtown San Antonio, where cultural experiences and delightful dining await. Embrace the warm hospitality of the region and create unforgettable memories in this beautiful part of Florida.

Branford: Located a mere 10km from O'Brien, Branford boasts a vibrant outdoor scene that attracts adventurers and nature enthusiasts alike. The town is known for its stunning scenery and plethora of recreational areas. Visitors can indulge in thrilling activities such as underwater sports or explore the nearby national state park. Branford’s natural landmarks, including a picturesque river and various water features, provide the perfect backdrop for a day of exploration and relaxation.
Mcalpin: Situated 11km away from O'Brien, Mcalpin is another gem in the region that offers a moderately seasonal influx of visitors. This city is a haven for those seeking outdoor experiences and scenic beauty. With access to recreational areas and adventure activities, guests can immerse themselves in the tranquil surroundings. The local attractions such as the river and national state park make Mcalpin an ideal destination for nature lovers and thrill-seekers alike.
Alton: A charming village located 19km from O'Brien, Alton captivates visitors with its serene landscapes and inviting atmosphere. Although its visitor numbers are relatively stable throughout the year, the peaks occur in March and October to November. Alton’s scenic river offers a peaceful retreat for those looking to unwind and enjoy the natural beauty of Florida. It’s a perfect spot for leisurely strolls and quiet reflection amidst the picturesque surroundings.

Things to do near O Brien

O'Brien, Florida, offers a delightful escape for outdoor enthusiasts, featuring stunning scenery and a range of adventurous activities. Visitors can enjoy jet skiing, leisurely river walks, and even a trip to the local bowling alley for some fun. With its recreational areas, O'Brien is perfect for those seeking adventure and relaxation in a beautiful natural setting.

Shopping

The nearest shopping option in O'Brien is the local market, where you can find handmade crafts and local produce. If you're up for a drive, head to Lake City Mall, about 32km away, featuring a range of popular retail stores and eateries for a more extensive shopping experience.

Recreation

In O'Brien, Florida, the Suwannee River State Park offers serene nature trails and picnic spots for relaxation. Nearby, the Healing Waters Spa provides rejuvenating treatments, allowing you to unwind amidst tranquil surroundings and enjoy a variety of holistic therapies tailored to refresh your mind and body.

Adventure

Experience the thrill of motor racing at North Florida Speedway, located 32km from O Brien. Feel the adrenaline as you watch high-speed races, enjoy the vibrant atmosphere, and immerse yourself in the excitement of this dynamic racing venue.

Nightlife

Experience the laid-back vibe at the O'Brien Cafe, where you can enjoy live music and a selection of local wines. For a lively atmosphere, visit the nearby O'Brien Sports Bar, serving up tasty pub grub and a variety of beers in a friendly setting.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for O Brien

The most and least expensive months on average to stay in a hotel: The cheapest months to stay in O Brien are January, August and November, where the prices are slightly lower. This is in comparison to March, May and October, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay in O Brien is Monday. The most expensive day to stay in O Brien is Saturday.
Find cheap hotels on Expedia: Utilise Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. To discover the most affordable prices and offers, arrange the price filter from lowest to highest.
Consider bundling your trip: You can potentially save money by combining your O'Brien hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near O Brien

O'Brien, Florida, is ideal for those seeking outdoor adventures and stunning scenery. Visitors can explore national and state parks, as well as picturesque rivers and lakes, making it a perfect destination for families and nature enthusiasts alike. With a variety of attractions that cater to outdoor experiences, O'Brien promises a memorable holiday filled with exploration and enjoyment of the natural beauty surrounding the area.

Suwannee River: A picturesque river located 10km from O Brien, the Suwannee River offers stunning outdoor scenery, perfect for leisurely canoeing or kayaking. Enjoy the tranquillity as you take in the lush surroundings and the vibrant wildlife that calls this area home.
Ichetucknee Springs State Park: Situated 18km away, this national park is a haven for adventure lovers. With its crystal-clear springs, visitors can indulge in tubing, snorkelling, or hiking along scenic trails, all while being enveloped in breathtaking natural beauty.
Branford Public Library: Just 8km from O Brien, this charming library provides a welcoming atmosphere for families. Explore a rich array of cultural resources and community events that foster learning and connection among visitors of all ages.

Best time to go to O Brien

The best time to visit O Brien is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	53.4°F (11.9°C)	Light Rain	Mostly Sunny	Average	Slightly Low
February	57.9°F (14.4°C)	Light Rain	Mostly Sunny	Average	Average
March	62.8°F (17.1°C)	Light Rain	Mostly Sunny	Average	Slightly High
April	69.1°F (20.6°C)	Light Rain	Mostly Sunny	Average	Average
May	75.4°F (24.1°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly High
June	80.2°F (26.8°C)	Light Rain	Mostly Sunny	Moderately High	Average
July	81.5°F (27.5°C)	Light Rain	Mostly Sunny	Moderately High	Average
August	81.3°F (27.4°C)	Light Rain	Mostly Sunny	Moderately High	Slightly Low
September	77.9°F (25.5°C)	Light Rain	Mostly Sunny	Average	Average
October	70.9°F (21.6°C)	No Rain	Mostly Sunny	Average	Slightly High
November	61.7°F (16.5°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly Low
December	57.4°F (14.1°C)	Light Rain	Mostly Sunny	Average	Average

The nearest major airports for your trip to O Brien

Accessing O'Brien, Florida is convenient through several nearby airports. Jacksonville International Airport (JAX) is situated 130km away, with nearby hotels such as the DoubleTree by Hilton Hotel Jacksonville Airport, located 483m from the airport, and the Hyatt Regency Jacksonville, 19km away. Tallahassee International Airport (TLH) is 140km from O'Brien, with quality accommodation options like the DoubleTree by Hilton Hotel Tallahassee and Hotel Duval, both 8km from the airport. Lastly, Gainesville Regional Airport (GNV) is just 76km away, featuring hotels like the DoubleTree by Hilton Gainesville and Hotel Indigo Gainesville-Celebration Pointe, both 13km from the airport.

Frequently asked questions

What is the best area to stay in O Brien?

The best area to stay in O'Brien, Florida, is along the Suwannee River, particularly around the public boat ramps and access points.This area is the main draw for visitors to O'Brien, as it provides direct access to the natural beauty and recreational opportunities of the Suwannee River. You'll find a scattering of accommodations, from holiday rentals to small, independent motels, often with direct riverfront access or just a short drive away. This allows for convenient enjoyment of activities like fishing, kayaking, and boating.Families will find this area particularly appealing due to the easy access to water-based activities. Many properties offer amenities like barbecue areas and space for children to play, making it simple to enjoy the outdoors together. The nearby Spirit of the Suwannee Music Park also hosts various events throughout the year, which can be a fun addition to a family holiday.For couples looking for a relaxed escape, staying by the river offers a peaceful setting. You can enjoy quiet evenings by the water, explore the river's springs, or simply unwind away from city life.

When is the best time to go to O Brien?

The best time to visit O'Brien, Florida, is typically during the spring (March to May) and autumn (September to November) months.During these periods, the weather is generally mild and pleasant, with comfortable temperatures, making it ideal for enjoying outdoor activities like swimming, fishing, and exploring the natural springs without the intense heat and humidity of summer or the cooler temperatures of winter. The spring also brings blooming wildflowers, adding to the area's natural beauty.For couples looking for a relaxing escape, these shoulder seasons offer a good balance of agreeable weather and fewer crowds compared to peak summer. You'll find it easier to enjoy the tranquility of the Ichetucknee Springs State Park or the Suwannee River without feeling overwhelmed by other visitors.Families travelling with children might also find these times more comfortable for outdoor adventures.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in O Brien.

How can I save on a hotel booking in O Brien with Expedia?

One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on O Brien hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

How much is the nightly rate for a hotel in O Brien?

Prices for hotels in O Brien often vary, but you can find a great deal from AU$93 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia

Activities in Gainesville

Book Hotels in O Brien on Expedia.com

Search O Brien hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in O Brien

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for O Brien hotels

1. Best Western Plus Lake City

2. Cindys Motel

3. Comfort Suites Lake City

4. Fairfield Inn & Suites Lake City

5. Hampton Inn & Suites Lake City

6. La Quinta Inn & Suite by Wyndham Lake City

7. Super 8 by Wyndham Lake City

8. Tru by Hilton Lake City

9. Holiday Inn Express & Suites Live Oak by IHG

10. Holiday Inn & Suites Lake City by IHG

11. Quality Inn Lake City

12. Suwannee River Rendezvous

13. Home2 Suites by Hilton Lake City

14. Quality Inn White Springs Suwanee

15. Americas Best Value Inn Lake City

16. Days Inn by Wyndham Lake City I-75

17. Courtyard By Marriott Lake City

18. Econo Lodge Live Oak

19. TownePlace Suites by Marriott Lake City

20. Suwannee River Retreat: Pet Friendly, Private Dock

Learn more about O Brien

Top O Brien Hotel Reviews

Recent Reviews in O Brien

Fairfield Inn & Suites Lake City

Hampton Inn & Suites Lake City

La Quinta Inn & Suite by Wyndham Lake City

Tru by Hilton Lake City

Comfort Suites Lake City

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Quality Inn & Suites Live Oak I-10 Exit 283

Hampton Inn & Suites Alachua I-75

More cheap accommodation in O Brien

Days Inn by Wyndham Lake City I-10

Quality Inn Lake City

Best Western Plus Lake City

Comfort Suites Lake City

Hampton Inn & Suites Alachua I-75

Tru by Hilton Lake City

Find out more about O Brien

Top reasons to visit O Brien

Find great hotels near O Brien

Where to stay near O Brien

Things to do near O Brien

Booking tips and Expedia advantages for O Brien

Find the best attractions near O Brien

Best time to go to O Brien

The nearest major airports for your trip to O Brien

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app